Immunogen
Synthesized peptide derived from human UBIP1 AA range: 264-314
Specificity
This antibody detects endogenous levels of UBIP1 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
function:Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.,induction:Induced by HIV-1 infection of lymphocytes.,similarity:Belongs to the grh/CP2 family. CP2 subfamily.,subunit:Interacts with TFCP2. Interacts with PIAS1, and is probably part of a complex containing TFCP2, UBP1
Human protein sequence Database
Q9NZI7
Mouse protein sequence database
Q811S7
Rat protein sequence database
Cellular localization
Nucleus .
Tissue expression
Expressed in adrenal tissue, JEG-3, NCI-H295A, Hep-G2 and HeLa cell lines.
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