Immunogen
Synthesized peptide derived from human DLGP4 AA range: 220-270
Specificity
This antibody detects endogenous levels of DLGP4 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
The product of this gene is a membrane-associated guanylate kinase found at the postsynaptic density in neuronal cells. It is a signaling molecule that can interact with potassium channels and receptors, as well as other signaling molecules. The protein encoded by this gene can interact with PSD-95 through its guanylate kinase domain and may be involved in clustering PSD-95 in the postsynaptic density region. The encoded protein is one of at least four similar proteins that have been found. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Function
function:May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane.,similarity:Belongs to the SAPAP family.,subunit:Interacts with DLG1 and DLG4/PSD-95.,
Gene Name
DLGAP4 DAP4 KIAA0964 SAPAP4
Human protein sequence Database
Q9Y2H0
Mouse protein sequence database
B1AZP2
Rat protein sequence database
P97839
Cellular localization
Membrane ; Peripheral membrane protein .
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