Immunogen
Synthesized peptide derived from human DNJA2 AA range: 309-359
Specificity
This antibody detects endogenous levels of DNJA2 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
The protein encoded by this gene belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus; a glycine/phenylalanine (G/F)-rich region; and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain. The product of this gene works as a cochaperone of Hsp70s in protein folding and mitochondrial protein import in vitro. [provided by RefSeq, Jul 2008],
Function
function:Co-chaperone of Hsc70.,similarity:Contains 1 CR-type zinc finger.,similarity:Contains 1 J domain.,
Gene Name
DNAJA2 CPR3 HIRIP4
Fields
>>Protein processing in endoplasmic reticulum
Human protein sequence Database
O60884
Mouse protein sequence database
Q9QYJ0
Rat protein sequence database
O35824
Cellular localization
Membrane ; Lipid-anchor .