Immunogen
Synthesized peptide derived from human TLL2 AA range: 268-318
Specificity
This antibody detects endogenous levels of TLL2 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes an astacin-like zinc-dependent metalloprotease and is a subfamily member of the metzincin family. Unlike other family members, a similar protein in mice does not cleave procollagen C-propeptides or chordin. [provided by RefSeq, Jul 2008],
Function
cofactor:Binds 1 zinc ion per subunit.,function:Protease which specifically processes pro-lysyl oxidase. Required for the embryonic development. Predominant protease, which in the development, influences dorsal-ventral patterning and skeletogenesis.,similarity:Belongs to the peptidase M12A family.,similarity:Contains 2 EGF-like domains.,similarity:Contains 5 CUB domains.,
Human protein sequence Database
Q9Y6L7
Mouse protein sequence database
Q9WVM6
Rat protein sequence database
Cellular localization
Secreted .
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