Immunogen
Synthesized peptide derived from human UE2NL AA range: 64-114
Specificity
This antibody detects endogenous levels of UE2NL at Human
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene is intronless and encodes a member of the ubiquitin-conjugating enzyme family. The protein product is 91% identical to ubiquitin-conjugating enzyme E2N, a multi-exon gene product. This locus represents a polymorphic pseudogene, where some individuals contain an allele that can encode a full-length protein, while others have a non-functional allele containing a premature stop codon (reference SNP rs237520) that truncates the coding sequence. [provided by RefSeq, Jun 2014],
Function
caution:Could be the product of a pseudogene. The potential active site Cys residue in position 88 is replaced by a Ser.,similarity:Belongs to the ubiquitin-conjugating enzyme family.,
Fields
>>Ubiquitin mediated proteolysis;>>Shigellosis
Human protein sequence Database
Q5JXB2
Mouse protein sequence database
Rat protein sequence database
Cellular localization
nucleus,cytoplasm,extracellular exosome,
Tissue expression
Expressed in epididymis (at protein level).