Immunogen
Synthesized peptide derived from human STK19 AA range: 89-139
Specificity
This antibody detects endogenous levels of STK19 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a serine/threonine kinase which localizes predominantly to the nucleus. Its specific function is unknown; it is possible that phosphorylation of this protein is involved in transcriptional regulation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6 and expresses two transcript variants. [provided by RefSeq, Jul 2008],
Function
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Divalent cations. Has a preference for manganese.,function:Seems to be a protein kinase. In vitro it can phosphorylate casein-alpha on serine and threonine residues and histones on serine residues.,similarity:Belongs to the STK19 family.,subunit:The N-terminus interacts with BAG1.,tissue specificity:Monocytes, hepatocytes, epithelial cells, T-and B-lymphocytes.,
Human protein sequence Database
P49842
Mouse protein sequence database
Q9JHN8
Rat protein sequence database
Cellular localization
Nucleus .
Tissue expression
Monocytes, hepatocytes, epithelial cells, T- and B-lymphocytes.
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