Immunogen
Synthesized peptide derived from human CPNE5 AA range: 191-241
Specificity
This antibody detects endogenous levels of CPNE5 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene is one of several genes that encode a calcium-dependent protein containing two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. More variants may exist, but their full-length natures could not be determined. [provided by RefSeq, Sep 2015],
Function
function:May function in membrane trafficking. Exhibits calcium-dependent phospholipid binding properties.,similarity:Belongs to the copine family.,similarity:Contains 1 VWFA domain.,similarity:Contains 2 C2 domains.,
Human protein sequence Database
Q9HCH3
Mouse protein sequence database
Q8JZW4
Rat protein sequence database
Cellular localization
Perikaryon . Cell projection .
Tissue expression
Expressed in the brain, heart, stomach, spleen, lymph node and testis (PubMed:12949241). Expressed in melanocytes (PubMed:23999003).
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