Immunogen
Synthesized peptide derived from human SF3B5 AA range: 1-50
Specificity
This antibody detects endogenous levels of SF3B5 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC-p 1:50-200. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the SF3B5 family.,subunit:Component of splicing factor SF3B which is composed of four subunits; SF3B4/SAP49, SF3B3/SAP130, SF3B2/SAP145, SF3B1/SAP155. SF3B associates with the splicing factor SF3A and a 12S RNA unit to form the U2 small nuclear ribonucleoproteins complex (U2 snRNP).,
Human protein sequence Database
Q9BWJ5
Mouse protein sequence database
Q923D4
Rat protein sequence database
Cellular localization
Nucleus .