Immunogen
Synthesized peptide derived from human FTMT AA range: 129-179
Specificity
This antibody detects endogenous levels of FTMT at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
catalytic activity:4 Fe(2+) + 4 H(+) + O(2) = 4 Fe(3+) + 2 H(2)O.,function:Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.,online information:Ferritin entry,similarity:Belongs to the ferritin family.,similarity:Contains 1 ferritin-like diiron domain.,subunit:Homo-oligomer of 24 subunits. The functional molecule is roughly spherical and contains a central cavity into which the polymeric mineral iron core is deposited.,tissue specificity:Detected in testis and erythroleukemia. Expression is very low or not detectable in brain, colon, heart, kidney, liver, lung, muscle, placental, spleen and small intestine.,
Human protein sequence Database
Q8N4E7
Mouse protein sequence database
Q9D5H4
Rat protein sequence database
Cellular localization
Mitochondrion .
Tissue expression
Detected in testis and erythroleukemia. Expression is very low or not detectable in brain, colon, heart, kidney, liver, lung, muscle, placental, spleen and small intestine.