Immunogen
Synthesized peptide derived from human CBPC4 AA range: 723-773
Specificity
This antibody detects endogenous levels of CBPC4 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
Polyglutamylation is a reversible posttranslational modification catalyzed by polyglutamylases that results in the addition of glutamate side chains on the modified protein. This gene encodes a glutamate decarboxylase that catalyzes the deglutamylation of polyglutamylated proteins. Mutations in this gene result in dominant late-onset Fuchs corneal dystrophy. [provided by RefSeq, Nov 2013],
Function
cofactor:Binds 1 zinc ion per subunit.,function:May play a role in the processing of tubulin.,similarity:Belongs to the peptidase M14 family.,
Human protein sequence Database
Q96MI9
Mouse protein sequence database
Q09M05
Rat protein sequence database
Cellular localization
Cytoplasm, cytosol .
Tissue expression
Expressed in corneal endothelium.