Immunogen
Synthesized peptide derived from human CRLS1 AA range: 61-111
Specificity
This antibody detects endogenous levels of CRLS1 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a member of the CDP-alcohol phosphatidyltransferase class-I family of proteins. The encoded enzyme catalyzes the synthesis of cardiolipin, a phospholipid component of mitochondrial membranes that is critical for mitochondrial function. [provided by RefSeq, Apr 2016],
Function
catalytic activity:2 Phosphatidylglycerol = diphosphatidylglycerol + glycerol.,function:Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.,similarity:Belongs to the CDP-alcohol phosphatidyltransferase class-I family.,tissue specificity:Highly expressed in tissues such as heart, skeletal muscle and liver.,
Gene Name
CRLS1 C20orf155 CLS1
Fields
>>Glycerophospholipid metabolism;>>Metabolic pathways
Human protein sequence Database
Q9UJA2
Mouse protein sequence database
Q80ZM8
Rat protein sequence database
Q5U2V5
Cellular localization
Mitochondrion inner membrane ; Multi-pass membrane protein .
Tissue expression
Highly expressed in tissues such as heart, skeletal muscle and liver.
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