Immunogen
Synthesized peptide derived from human CDY2 AA range: 434-484
Specificity
This antibody detects endogenous levels of CDY2 at Human
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This intronless gene encodes a protein containing a chromodomain and a histone acetyltransferase catalytic domain. Chromodomain proteins are components of heterochromatin-like complexes and can act as gene repressors. This protein is localized to the nucleus of late spermatids where histone hyperacetylation takes place. Histone hyperacetylation is thought to facilitate the transition in which protamines replace histones as the major DNA-packaging protein. Two nearly identical copies of this gene are found in a palindromic region on chromosome Y; this record represents the telomeric copy. Chromosome Y also contains a pair of closely related genes in another more telomeric palindrome as well as several related pseudogenes. [provided by RefSeq, Jul 2008],
Function
catalytic activity:Acetyl-CoA + histone = CoA + acetylhistone.,function:May have histone acetyltransferase activity.,similarity:Contains 1 chromo domain.,tissue specificity:Testis specific.,
Gene Name
CDY2A CDY2; CDY2B
Human protein sequence Database
Q9Y6F7
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Nucleus .
Tissue expression
Testis specific.
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