Immunogen
Synthesized peptide derived from human PLXA3 AA range: 1728-1778
Specificity
This antibody detects endogenous levels of PLXA3 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a member of the plexin class of proteins. The encoded protein is a class 3 semaphorin receptor, and may be involved in cytoskeletal remodeling and as well as apoptosis. Studies of a similar gene in zebrafish suggest that it is important for axon pathfinding in the developing nervous system. This gene may be associated with tumor progression. [provided by RefSeq, Aug 2013],
Function
function:Putative receptor involved in the development of neural and epithelial tissues.,similarity:Belongs to the plexin family.,similarity:Contains 1 Sema domain.,similarity:Contains 4 IPT/TIG domains.,tissue specificity:Predominant in neural tissue during development (By similarity); widely expressed in adult tissue.,
Gene Name
PLXNA3 PLXN4 SEX
Human protein sequence Database
P51805
Mouse protein sequence database
P70208
Rat protein sequence database
D3ZPX4
Cellular localization
Cell membrane ; Single-pass type I membrane protein .
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