Immunogen
Synthesized peptide derived from human XAF1 AA range: 47-97
Specificity
This antibody detects endogenous levels of human XAF1
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:1000-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Gene Name
XAF1 BIRC4BP XIAPAF1
Protein name
XIAP-associated factor 1 (BIRC4-binding protein)
Human protein sequence Database
Q6GPH4
Mouse protein sequence database
Q5NBU8
Rat protein sequence database
Cellular localization
Cytoplasm. Nucleus. Mitochondrion. Found in the cytoplasm and nucleus of placental syncytiotrophoblasts. Translocates to mitochondria upon TNF-alpha treatment.; [Isoform 1]: Nucleus.; [Isoform 5]: Nucleus.
Tissue expression
Widely expressed. Expression is frequently down-regulated in cancer cell lines. Isoform 5 is widely expressed. Expressed in placenta (at protein level).