Immunogen
Synthesized peptide derived from human ZC12D AA range: 87-137
Specificity
This antibody detects endogenous levels of human ZC12D
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:1000-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Gene Name
ZC3H12D C6orf95 MCPIP4 TFL
Protein name
Probable ribonuclease ZC3H12D (EC 3.1.-.-) (MCP-induced protein 4) (Transformed follicular lymphoma) (Zinc finger CCCH domain-containing protein 12D) (p34)
Human protein sequence Database
A2A288
Mouse protein sequence database
Q8BIY3
Rat protein sequence database
Cellular localization
Cytoplasm, P-body . Colocalizes with ZC3H12A in GW bodies (GWBs) (PubMed:26134560). .; [Isoform 1]: Cytoplasm. Localized as discrete granules. Colocalized with mRNA-processing body markers, AGO2 and DCP1A, but not with a stress granule maker, TIA1, in the cytoplasm.; [Isoform 3]: Cytoplasm. Nucleus.
Tissue expression
Expressed in normal human lymphocytes but defective in some leukemia/lymphoma cell lines.