Immunogen
Synthesized peptide derived from human EHD1 AA range: 49-99
Specificity
This antibody detects endogenous levels of human EHD1
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:1000-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Gene Name
EHD1 PAST PAST1 CDABP0131
Protein name
EH domain-containing protein 1 (PAST homolog 1) (hPAST1) (Testilin)
Human protein sequence Database
Q9H4M9
Mouse protein sequence database
Q9WVK4
Rat protein sequence database
Q641Z6
Cellular localization
Recycling endosome membrane ; Peripheral membrane protein ; Cytoplasmic side . Early endosome membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection, cilium membrane ; Peripheral membrane protein ; Cytoplasmic side . Preferentially associates with tubular recycling endosomes (PubMed:15020713, PubMed:17233914, PubMed:19864458, PubMed:23596323). Colocalizes with FER1L5 at plasma membrane in myoblasts and myotubes (By similarity). Localizes to the ciliary pocket from where the cilium protrudes (PubMed:25686250). Colocalizes with BACE1 in tubulovesicular cytoplasmic membranes. Colocalizes with BACE1 and APP amyloid beta proteins in hippocampal mossy fiber terminals (By similarity). .
Tissue expression
Highly expressed in testis.
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