Immunogen
Synthesized peptide derived from human KAZRN AA range: 125-175
Specificity
This antibody detects endogenous levels of human KAZRN
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:1000-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Gene Name
KAZN KAZ KIAA1026 HRIHFB2003
Human protein sequence Database
Q674X7
Mouse protein sequence database
Q69ZS8
Rat protein sequence database
Q5FWS6
Cellular localization
Cytoplasm, cytoskeleton .; [Isoform 2]: Cytoplasm. Cell junction, desmosome. Nucleus. Observed at the apical plasma membrane of keratinocytes. Partially colocalizes with PPL and DP at desmosomes, and with PP at the interdesmosomal plasma membrane. Colocalizes with cortical actin-based membrane structures.; [Isoform 3]: Cytoplasm. Cell junction, desmosome. Nucleus. Observed at the apical plasma membrane of keratinocytes. Partially colocalizes with PPL and DP at desmosomes, and with PP at the interdesmosomal plasma membrane. Colocalizes with cortical actin-based membrane structures.; [Isoform 4]: Cytoplasm. Cell junction, desmosome. Nucleus. Observed at the apical plasma membrane of keratinocytes. Partially colocalizes with PPL and DP at desmosomes, and with PP at the interdesmosomal plasma
Tissue expression
Isoform 2, isoform 3 and isoform 4 are expressed in several cell lines including keratinocytes and bladder and epidermoid carcinoma (at protein level). Isoform 2, isoform 3 and isoform 4 are expressed in hair follicle and interfollicular epidermis (at protein level).