Immunogen
Synthesized peptide derived from human PLCZ1 AA range: 520-570
Specificity
This antibody detects endogenous levels of human PLCZ1
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:1000-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Protein name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-zeta-1) (Phospholipase C-zeta-1) (PLC-zeta-1) (Testis-development protein NYD-SP27)
Fields
>>Inositol phosphate metabolism;>>Metabolic pathways;>>Calcium signaling pathway;>>Phosphatidylinositol signaling system;>>Oocyte meiosis;>>Thyroid hormone signaling pathway;>>Shigellosis
Human protein sequence Database
Q86YW0
Mouse protein sequence database
Q8K4D7
Rat protein sequence database
Q5FX52
Cellular localization
Nucleus . Cytoplasm, perinuclear region . Exhibits alternative cytoplasmic/nuclear localization during development. Translocates from the pronucleus into cytoplasm upon nuclear envelope breakdown for mitosis and localizes again to the pronucleus at interphase following meiosis and mitosis (By similarity). .
Tissue expression
Expressed specifically in testis and sperm. Weakly expressed in pancreatic-duct cells. Up-regulated in pancreatic-duct cells from patients with cystic fibrosis.
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