Immunogen
Synthesized peptide derived from human PI3R4 AA range: 170-220
Specificity
This antibody detects endogenous levels of human PI3R4
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:1000-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Protein name
Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein)
Fields
>>Autophagy - other;>>Autophagy - animal;>>Apelin signaling pathway;>>Alzheimer disease;>>Amyotrophic lateral sclerosis;>>Huntington disease;>>Spinocerebellar ataxia;>>Pathways of neurodegeneration - multiple diseases;>>Shigellosis
Human protein sequence Database
Q99570
Mouse protein sequence database
Q8VD65
Rat protein sequence database
P0C0R5
Cellular localization
Late endosome . Cytoplasmic vesicle, autophagosome . Membrane ; Lipid-anchor . As component of the PI3K complex I localized to pre-autophagosome structures. As component of the PI3K complex II localized predominantly to endosomes. Localizes also to discrete punctae along the ciliary axoneme (By similarity). .
Tissue expression
Ubiquitously expressed.
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