Immunogen
Synthesized peptide derived from human SHLB1 AA range: 45-95
Specificity
This antibody detects endogenous levels of human SHLB1
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:1000-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Gene Name
SH3GLB1 KIAA0491 CGI-61
Protein name
Endophilin-B1 (Bax-interacting factor 1) (Bif-1) (SH3 domain-containing GRB2-like protein B1)
Fields
>>Autophagy - animal;>>Endocytosis
Human protein sequence Database
Q9Y371
Mouse protein sequence database
Q9JK48
Rat protein sequence database
Q6AYE2
Cellular localization
Cytoplasm . Golgi apparatus membrane ; Peripheral membrane protein . Mitochondrion outer membrane ; Peripheral membrane protein . Cytoplasmic vesicle, autophagosome membrane . Midbody . Association with the Golgi apparatus depends on the cell type (By similarity). Following starvation colocalizes with ATG5 and LC3 autophagy-related protein(s)on autophagosomal membranes (PubMed:17891140). .
Tissue expression
Highly expressed in heart, skeletal muscle, kidney and placenta. Detected at lower levels in brain, colon, thymus, spleen, liver, small intestine, lung and peripheral blood leukocytes.
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