Immunogen
Synthesized peptide derived from human SPEF2. AA range 1790-1820
Specificity
This antibody detects endogenous levels of human SPEF2
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:1000-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Gene Name
SPEF2 KIAA1770 KPL2
Protein name
Sperm flagellar protein 2 (Protein KPL2)
Human protein sequence Database
Q9C093
Mouse protein sequence database
Q8C9J3
Rat protein sequence database
Q9R095
Cellular localization
Cell projection, cilium, flagellum . Cytoplasm . Golgi apparatus . Shows dynamic localization in developing spermatozoa. Localizes to the manchette in step 10-12 elongating spermatids. Detected in the basal body and neck area of step 13-14 spermatids. Localizes to the midpiece of the sperm tail in step 15-16 spermatids. During the epididymal transport of spermatozoa, expression in the sperm tail reduces and becomes concentrated at the distal part of the midpiece. Detected in the Golgi apparatus of late spermatocytes and round spermatids. Detected in the cytoplasm of Sertoli cells. .