Immunogen
Synthesized peptide derived from human TBC24 AA range: 12-62
Specificity
This antibody detects endogenous levels of human TBC24
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:1000-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Gene Name
TBC1D24 KIAA1171
Protein name
TBC1 domain family member 24
Human protein sequence Database
Q9ULP9
Mouse protein sequence database
Q3UUG6
Rat protein sequence database
Cellular localization
Cell membrane ; Peripheral membrane protein . Cytoplasm . Cytoplasmic vesicle membrane . Cell junction, synapse, presynapse . Mainly cytoplasmatic with partial expression at the plasma membrane (PubMed:20727515). Associates with certain types of membrane phosphoinositides, preferentially those phosphorylated at the D5 position of the inositol ring such as phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3) (By similarity). .
Tissue expression
Highest expression in brain.