Immunogen
Synthesized peptide derived from human LBR AA range: 411-461
Specificity
This antibody detects endogenous levels of human LBR
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:1000-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Protein name
Lamin-B receptor (Integral nuclear envelope inner membrane protein) (LMN2R)
Fields
>>Steroid biosynthesis;>>Metabolic pathways
Human protein sequence Database
Q14739
Mouse protein sequence database
Q3U9G9
Rat protein sequence database
O08984
Cellular localization
Nucleus inner membrane ; Multi-pass membrane protein . Endoplasmic reticulum membrane . Cytoplasm . Nucleus . Nucleus; nuclear rim. .
Tissue expression
Expressed in the bone marrow, liver, heart, adrenal gland, lung, placenta and uterus (PubMed:16784888). Expressed in osteoclasts and osteoblast-like cells (PubMed:21327084).