Immunogen
Synthesized peptide derived from human BORA (Phospho-Ser497)
Specificity
This antibody detects endogenous levels of BORA (Phospho-Ser497) at Human, Mouse,Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, and 0.209% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
BORA is an activator of the protein kinase Aurora A (AURKA; MIM 603072), which is required for centrosome maturation, spindle assembly, and asymmetric protein localization during mitosis (Hutterer et al., 2006 [PubMed 16890155]).[supplied by OMIM, Mar 2008],
Function
function:Required for the activation of Aurora-A (AURKA/STK6) at the onset of mitosis.,PTM:Phosphorylated by AURKA/STK6.,similarity:Belongs to the BORA family.,subunit:Interacts with AURKA/STK6.,
Protein name
BORA (Phospho-Ser497)
Other name
Protein aurora borealis (HsBora)
Human protein sequence Database
Q6PGQ7
Mouse protein sequence database
Q8BS90
Rat protein sequence database
Q5M864
Cellular localization
cytosol,meiotic spindle,
Tissue expression
Bone marrow,Leiomyosarcoma,Rhabdomyosarcoma,Small intestine,Testis carcinom
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