Molecular weight (DA)
15kD
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human BATF3. AA range:1-50
Specificity
BATF3 Polyclonal Antibody detects endogenous levels of BATF3 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the basic leucine zipper protein family. The encoded protein functions as a transcriptional repressor when heterodimerizing with JUN. The protein may play a role in repression of interleukin-2 and matrix metalloproteinase-1 transcription.[provided by RefSeq, Feb 2009],
Function
function:Functions as a negative regulator of AP-1-mediated transcription by heterodimerizing with JUN and binding DNA at 12-O-tetradecanoylphorbol-13-acetate response elements (TRE) (consensus: 5'-TGA[CG]TCA-3'). Represses IL2 and MMP1 promoter activities.,similarity:Belongs to the bZIP family.,similarity:Contains 1 bZIP domain.,subunit:Interacts with JUN.,
Protein name
Basic leucine zipper transcriptional factor ATF-like 3
Other name
BATF3; SNFT; Basic leucine zipper transcriptional factor ATF-like 3; B-ATF-3; 21 kDa small nuclear factor isolated from T-cells; Jun dimerization protein p21SNFT
Fields
>>PD-L1 expression and PD-1 checkpoint pathway in cancer
Human protein sequence Database
Q9NR55
Mouse protein sequence database
Q9D275
Rat protein sequence database
P97876
Cellular localization
Nucleus .