Immunogen
Synthetic peptide from human protein at AA range: 31-80
Specificity
The antibody detects endogenous CD300e
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC-p 1:50-200, ELISA 1:10000-20000. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
CD300e molecule(CD300E) Homo sapiens This gene encodes a member of the CD300 glycoprotein family of cell surface proteins expressed on myeloid cells. The protein interacts with the TYRO protein tyrosine kinase-binding protein and is thought to act as an activating receptor. [provided by RefSeq, Nov 2012],
Function
function:Probably acts as an activating receptor.,PTM:N-glycosylated.,similarity:Belongs to the CD300 family.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with TYROBP.,tissue specificity:Present on the surface of mature hematopoietic cells of the monocyte and myeloid lineages (at protein level).,
Gene Name
CD300E CD300LE CLM2 CMRF35A5 IREM2
Protein name
CMRF35-like molecule 2 (CLM-2) (CD300 antigen-like family member E) (CMRF35-A5) (Immune receptor expressed on myeloid cells 2) (IREM-2) (Polymeric immunoglobulin receptor 2) (PIgR-2) (PIgR2) (Poly-Ig
Other name
CMRF35-like molecule 2 (CLM-2;CD300 antigen-like family member E;CMRF35-A5;Immune receptor expressed on myeloid cells 2;IREM-2;Polymeric immunoglobulin receptor 2;PIgR-2;PIgR2;Poly-Ig receptor 2;CD antigen CD300e)
Human protein sequence Database
Q496F6
Mouse protein sequence database
Q8K249
Rat protein sequence database
Cellular localization
Cell membrane; Single-pass type I membrane protein.
Tissue expression
Present on the surface of mature hematopoietic cells of the monocyte and myeloid lineages (at protein level).
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