Immunogen
Synthetic peptide from human protein at AA range: 90-125
Specificity
The antibody detects endogenous MIG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC-p 1:50-200, ELISA 1:10000-20000. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This antimicrobial gene encodes a protein thought to be involved in T cell trafficking. The encoded protein binds to C-X-C motif chemokine 3 and is a chemoattractant for lymphocytes but not for neutrophils. [provided by RefSeq, Sep 2014],
Function
function:Cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. Chemotactic for activated T-cells. Binds to CXCR3.,induction:By interferon gamma. The induction is enhanced by TNF-alpha in dermal fibroblasts and vein endothelial cells.,online information:CXCL9 entry,similarity:Belongs to the intercrine alpha (chemokine CxC) family.,
Gene Name
CXCL9 CMK MIG SCYB9
Protein name
C-X-C motif chemokine 9 (Gamma-interferon-induced monokine) (Monokine induced by interferon-gamma) (HuMIG) (MIG) (Small-inducible cytokine B9)
Other name
C-X-C motif chemokine 9 (Gamma-interferon-induced monokine;Monokine induced by interferon-gamma;HuMIG;MIG;Small-inducible cytokine B9)
Fields
>>Cytokine-cytokine receptor interaction;>>Viral protein interaction with cytokine and cytokine receptor;>>Chemokine signaling pathway;>>Toll-like receptor signaling pathway
Human protein sequence Database
Q07325
Mouse protein sequence database
P18340
Rat protein sequence database
Cellular localization
Secreted.
Tissue expression
Keratinocyte,Monocyte,Placenta,Skin,
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