Immunogen
Synthesized peptide derived from human RPAB4 AA range: 1-50
Specificity
This antibody detects endogenous levels of human RPAB4
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC-p 1:50-200, ELISA(peptide)1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Background
This gene encodes one of the smallest subunits of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases. [provided by RefSeq, Jul 2008],
Function
function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and a small RNAs, such as 5S rRNA and tRNAs, respectively.,similarity:Belongs to the archaeal rpoP/eukaryotic RPC10 RNA polymerase subunit family.,subunit:Component of the RNA polymerase I (Pol I), RNA polymerase II (Pol II) and RNA polymerase III (Pol III) complexes consisting of at least 13, 12 and 17 subunits, respectively.,
Other name
DNA-directed RNA polymerases I, II, and III subunit RPABC4 (RNA polymerases I, II, and III subunit ABC4;ABC10-alpha;DNA-directed RNA polymerase II subunit K;RNA polymerase II 7.0 kDa subunit;RPB7.0;RPB10alpha)
Fields
>>RNA polymerase;>>Cytosolic DNA-sensing pathway;>>Huntington disease
Human protein sequence Database
P53803
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Nucleus .
Tissue expression
Ovary,Placenta,
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