Immunogen
Synthesized peptide derived from human WIT1 AA range: 20-100
Specificity
This antibody detects endogenous levels of human WIT1
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Background
This gene is located upstream of the Wilms tumor 1 (WT1) gene; these two genes are bi-directionally transcribed from the same promoter region. This gene is imprinted in kidney, with preferential expression from the paternal allele. Imprinting defects at chromosome 11p13 may contribute to tumorigenesis. [provided by RefSeq, May 2014],
Function
cell proliferation,
Other name
Putative Wilms tumor upstream neighbor 1 gene protein (WIT-1;Wilms tumor-associated antisense RNA)
Human protein sequence Database
Q06250
Mouse protein sequence database
Rat protein sequence database
Tissue expression
Kidney,Placenta,Uterus,