Immunogen
Synthesized peptide derived from human SERP1 AA range: 20-100
Specificity
This antibody detects endogenous levels of human SERP1
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC-p 1:50-200, ELISA(peptide)1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Background
function:Interacts with target proteins during their translocation into the lumen of the endoplasmic reticulum. Protects unfolded target proteins against degradation during ER stress. May facilitate glycosylation of target proteins after termination of ER stress. May modulate the use of N-glycosylation sites on target proteins.,similarity:Belongs to the RAMP4 family.,subunit:Interacts with SEC61B, SEC61A1 and the SEC61 complex. Interacts with CANX.,
Function
function:Interacts with target proteins during their translocation into the lumen of the endoplasmic reticulum. Protects unfolded target proteins against degradation during ER stress. May facilitate glycosylation of target proteins after termination of ER stress. May modulate the use of N-glycosylation sites on target proteins.,similarity:Belongs to the RAMP4 family.,subunit:Interacts with SEC61B, SEC61A1 and the SEC61 complex. Interacts with CANX.,
Other name
Stress-associated endoplasmic reticulum protein 1 (Ribosome-attached membrane protein 4)
Human protein sequence Database
Q9Y6X1
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Membrane; Single-pass type IV membrane protein. Endoplasmic reticulum membrane ; Single-pass membrane protein ; Cytoplasmic side .
Tissue expression
Adrenal gland,Testis,Uterus,
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