Immunogen
Synthesized peptide derived from human ZN274 AA range: 111-161
Specificity
This antibody detects endogenous levels of ZN274 at Human
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a zinc finger protein containing five C2H2-type zinc finger domains, one or two Kruppel-associated box A (KRAB A) domains, and a leucine-rich domain. The encoded protein has been suggested to be a transcriptional repressor. It localizes predominantly to the nucleolus. Alternatively spliced transcript variants encoding different isoforms exist. These variants utilize alternative polyadenylation signals. [provided by RefSeq, Jul 2008],
Function
alternative products:Experimental confirmation may be lacking for some isoforms,function:Seems to function as a transcriptional repressor.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 1 KRAB domain.,similarity:Contains 1 SCAN box domain.,similarity:Contains 2 KRAB domains.,similarity:Contains 5 C2H2-type zinc fingers.,
Gene Name
ZNF274 ZKSCAN19 SP2114
Fields
>>Neurotrophin signaling pathway
Human protein sequence Database
Q96GC6
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Cytoplasm . Nucleus, nucleolus .
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