Immunogen
Synthesized peptide derived from human KDEL1 AA range: 4-54
Specificity
This antibody detects endogenous levels of KDEL1 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a protein product localized to the lumen of the endoplasmic reticulum. As a member of the endoplasmic reticulum protein family the encoded protein contains a Lys-Asp-Glu-Leu or KDEL motif located at the extreme C-terminus which prevents all endoplasmic reticulum resident proteins from being secreted. Proteins carrying this motif are bound by a receptor in the Golgi apparatus so that the receptor-ligand complex returns to the endoplasmic reticulum. A processed non-transcribed pseudogene located in an intron of a sodium transporter gene on chromosome 5 has been defined for this gene. This gene has multiple transcript variants which are predicted to encode distinct isoforms. [provided by RefSeq, Jan 2016],
Function
PTM:N-glycosylated.,similarity:Belongs to the KDELC family.,similarity:Contains 1 filamin repeat.,
Gene Name
KDELC1 EP58 UNQ1910/PRO4357
Human protein sequence Database
Q6UW63
Mouse protein sequence database
Q9JHP7
Rat protein sequence database
Cellular localization
Endoplasmic reticulum lumen .
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