Immunogen
Synthesized peptide derived from human ILVBL AA range: 87-137
Specificity
This antibody detects endogenous levels of ILVBL at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
The protein encoded by this gene shares similarity with several thiamine pyrophosphate-binding proteins identified in bacteria, yeast, and plants. The highest degree of similarity is found with bacterial acetolactate synthases (AHAS), which are enzymes that catalyze the first step in branched-chain amino acid biosynthesis. [provided by RefSeq, Jul 2008],
Function
cofactor:Binds 1 magnesium ion per subunit.,cofactor:Binds 1 thiamine pyrophosphate per subunit.,sequence caution:Sequence of unknown origin at the C-terminus.,sequence caution:Translation N-terminally extended.,similarity:Belongs to the TPP enzyme family.,tissue specificity:Expressed in all tissues tested, with highest expression in heart, pancreas and placenta.,
Human protein sequence Database
A1L0T0
Mouse protein sequence database
Q8BU33
Rat protein sequence database
Cellular localization
Endoplasmic reticulum membrane ; Single-pass membrane protein .
Tissue expression
Expressed in all tissues tested, with highest expression in heart, pancreas and placenta.