Immunogen
Synthesized peptide derived from human FCGBP AA range: 1806-1856
Specificity
This antibody detects endogenous levels of FCGBP at Human
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC-p 1:50-200. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
domain:The N-terminal IgGFc-binding region is primate-specific.,function:May be involved in the maintenance of the mucosal structure as a gel-like component of the mucosa.,similarity:Contains 12 TIL (trypsin inhibitory-like) domains.,similarity:Contains 13 VWFD domains.,subunit:Interacts with the Fc portion of IgG and with MUC2.,tissue specificity:Mainly expressed in placenta and colon epithelium. Expressed in thyroid, and down-regulated in thyroid carcinomas. Present in serum, with higher levels in patients with various autoimmune diseases (at protein level).,
Human protein sequence Database
Q9Y6R7
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Secreted .
Tissue expression
Mainly expressed in placenta and colon epithelium. Expressed in thyroid, and down-regulated in thyroid carcinomas. Present in serum, with higher levels in patients with various autoimmune diseases (at protein level).