Immunogen
Synthesized peptide derived from human K1731 AA range: 208-258
Specificity
This antibody detects endogenous levels of K1731 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC-p 1：50-200. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
sequence caution:Translation N-terminally shortened.,similarity:Contains 7 LRR (leucine-rich) repeats.,
Human protein sequence Database
Q9C0D2
Mouse protein sequence database
Q8BQ48
Rat protein sequence database
A4L9P8
Cellular localization
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle . Cytoplasm, cytoskeleton . Associates with both of the converted centrioles during G1 but becomes more enriched at the newly formed daughter (or unconverted) centrioles during S, G2, and early M phases (PubMed:25131205, PubMed:32060285). In early S phase, localized at the procentriolar microtubule wall and enriched at the proximal ends of the centrioles in CENPJ- and CEP135-dependent manner (PubMed:27185865). Colocalizes with SASS6 and CEP250 proteins (PubMed:25131205). Colocalizes with CEP135 and CEP192 at the centrosomes (PubMed:27185865). Associates with interphase microtubules and mitotic spindles (PubMed:
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