Immunogen
Synthesized peptide derived from human MPPB AA range: 92-142
Specificity
This antibody detects endogenous levels of MPPB at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene is a member of the peptidase M16 family and encodes a protein with a zinc-binding motif. This protein is located in the mitochondrial matrix and catalyzes the cleavage of the leader peptides of precursor proteins newly imported into the mitochondria, though it only functions as part of a heterodimeric complex. [provided by RefSeq, Jul 2008],
Function
catalytic activity:Release of N-terminal transit peptides from precursor proteins imported into the mitochondrion, typically with Arg in position P2.,cofactor:Binds 1 zinc ion per subunit.,function:Cleaves presequences (transit peptides) from mitochondrial protein precursors.,similarity:Belongs to the peptidase M16 family.,subunit:Heterodimer of alpha and beta subunits.,
Human protein sequence Database
O75439
Mouse protein sequence database
Q9CXT8
Rat protein sequence database
Q03346
Cellular localization
Mitochondrion matrix .
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