Immunogen
Synthesized peptide derived from human GNPI1 AA range: 109-159
Specificity
This antibody detects endogenous levels of GNPI1 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
Glucosamine-6-phosphate deaminase (EC 3.5.99.6) is an allosteric enzyme that catalyzes the reversible conversion of D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium (Arreola et al., 2003 [PubMed 12965206]).[supplied by OMIM, Jan 2010],
Function
catalytic activity:D-glucosamine 6-phosphate + H(2)O = D-fructose 6-phosphate + NH(3).,function:Seems to trigger calcium oscillations in mammalian eggs. These oscillations serve as the essential trigger for egg activation and early development of the embryo.,similarity:Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.,subunit:Homohexamer.,
Gene Name
GNPDA1 GNPI HLN KIAA0060
Fields
>>Amino sugar and nucleotide sugar metabolism;>>Metabolic pathways
Human protein sequence Database
P46926
Mouse protein sequence database
O88958
Rat protein sequence database
Cellular localization
Cytoplasm .
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