Immunogen
Synthesized peptide derived from human LRC4C AA range: 524-574
Specificity
This antibody detects endogenous levels of LRC4C at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
NGL1 is a specific binding partner for netrin G1 (NTNG1; MIM 608818), which is a member of the netrin family of axon guidance molecules (Lin et al., 2003 [PubMed 14595443]).[supplied by OMIM, Mar 2008],
Gene Name
LRRC4C KIAA1580 NGL1 UNQ292/PRO331
Fields
>>Axon guidance;>>Cell adhesion molecules
Human protein sequence Database
Q9HCJ2
Mouse protein sequence database
Q8C031
Rat protein sequence database
Cellular localization
Cell junction, synapse, postsynaptic cell membrane ; Single-pass type I membrane protein .
Tissue expression
Highly expressed in the cerebral cortex, including frontal, parietal and occipital lobes. Putamen, amygdala, hippocampus and medulla oblongata show moderate expression. Caudate nucleus and thalamus express small amounts, whereas other brain regions show very weak or no expression.
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