Immunogen
Synthesized peptide derived from human PEBP4 AA range: 132-182
Specificity
This antibody detects endogenous levels of PEBP4 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
The phosphatidylethanolamine (PE)-binding proteins, including PEBP4, are an evolutionarily conserved family of proteins with pivotal biologic functions, such as lipid binding and inhibition of serine proteases (Wang et al., 2004 [PubMed 15302887]).[supplied by OMIM, Dec 2008],
Function
function:Seems to promote cellular resistance to TNF-induced apoptosis by inhibiting activation of the Raf-1/MEK/ERK pathway, JNK and phosphatidylethanolamine externalization.,similarity:Belongs to the phosphatidylethanolamine-binding protein family.,tissue specificity:Ubiquitously expressed. Highly expressed in tumor cells.,
Gene Name
PEBP4 CORK1 UNQ1933/PRO4408
Human protein sequence Database
Q96S96
Mouse protein sequence database
Q9D9G2
Rat protein sequence database
Cellular localization
Secreted .