Immunogen
Synthesized peptide derived from human URAD AA range: 80-130
Specificity
This antibody detects endogenous levels of URAD at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
catalytic activity:5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate = (S)-allantoin + CO(2).,caution:Could be the product of a pseudogene. In primates the genes coding for the enzymes for the degradation of uric acid were inactivated and converted to pseudogenes.,function:Catalyzes the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin .,pathway:Purine metabolism; uric acid degradation; (S)-allantoin from uric acid: step 3/3.,similarity:Belongs to the OHCU decarboxylase family.,tissue specificity:Apparently not expressed.,
Fields
>>Purine metabolism;>>Metabolic pathways
Human protein sequence Database
A6NGE7
Mouse protein sequence database
Q283N4
Rat protein sequence database
Cellular localization
Peroxisome .
Tissue expression
Apparently not expressed.
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