Immunogen
Synthesized peptide derived from human TECT2 AA range: 427-477
Specificity
This antibody detects endogenous levels of TECT2 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a type I membrane protein that belongs to the tectonic family. Studies in mice suggest that this protein may be involved in hedgehog signaling, and essential for ciliogenesis. Mutations in this gene are associated with Meckel syndrome type 8. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],
Function
similarity:Belongs to the tectonic family.,
Gene Name
TCTN2 C12orf38 TECT2
Human protein sequence Database
Q96GX1
Mouse protein sequence database
Q2MV57
Rat protein sequence database
Q3B7D3
Cellular localization
Membrane ; Single-pass type I membrane protein . Cytoplasm, cytoskeleton, cilium basal body . Localizes at the transition zone, a region between the basal body and the ciliary axoneme. .
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