Immunogen
Synthesized peptide derived from human M4A6A AA range: 8-58
Specificity
This antibody detects endogenous levels of M4A6A at Human
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. The gene encoding this protein is localized to 11q12.1, among a cluster of family members. Alternative splicing of this gene results in several transcript variants that encode different protein isoforms. [provided by RefSeq, Oct 2011],
Function
function:May be involved in signal transduction as a component of a multimeric receptor complex.,similarity:Belongs to the MS4A family.,tissue specificity:Variable expression in some B-cell, myelomonocytic, and erythroleukemia cell lines.,
Gene Name
MS4A6A 4SPAN3 CD20L3 MS4A6 CDA01 MSTP090
Human protein sequence Database
Q9H2W1
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Membrane; Multi-pass membrane protein.
Tissue expression
Variable expression in some B-cell, myelomonocytic, and erythroleukemia cell lines.