Immunogen
Synthesized peptide derived from human RCBT2 AA range: 53-103
Specificity
This antibody detects endogenous levels of RCBT2 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a protein containing two C-terminal BTB/POZ domains that is related to regulator of chromosome condensation (RCC). The encoded protein may act as a guanine nucleotide exchange factor. This gene is observed to be lost or underexpressed in prostate cancers. There is a pseudogene of this gene on chromosome 10. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013],
Function
similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 2 BTB (POZ) domains.,similarity:Contains 6 RCC1 repeats.,
Gene Name
RCBTB2 CHC1L RLG
Human protein sequence Database
O95199
Mouse protein sequence database
Q99LJ7
Rat protein sequence database
Q6P798
Cellular localization
Cytoplasmic vesicle, secretory vesicle, acrosome . Mainly found in the acrosomal cap region. .
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