Immunogen
Synthesized peptide derived from human TRI69 AA range: 202-252
Specificity
This antibody detects endogenous levels of TRI69 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a member of the RING-B-box-coiled-coil (RBCC) family and encodes a protein with an N-terminal RING finger motif, a PRY domain and a C-terminal SPRY domain. The mouse ortholog of this gene is specifically expressed in germ cells at the round spermatid stages during spermatogenesis and, when overexpressed, induces apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008],
Function
function:May play a role in apoptosis.,PTM:Phosphorylated. Phosphorylation is necessary for nuclear localization.,similarity:Belongs to the TRIM/RBCC family.,similarity:Contains 1 B30.2/SPRY domain.,similarity:Contains 1 RING-type zinc finger.,subunit:Interacts with PML.,
Gene Name
TRIM69 RNF36 HSD-34 HSD34
Human protein sequence Database
Q86WT6
Mouse protein sequence database
Q80X56
Rat protein sequence database
Q5BK82
Cellular localization
Cytoplasm . Nucleus . Nucleus speckle .
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