Immunogen
Synthesized peptide derived from human DPEP2 AA range: 94-144
Specificity
This antibody detects endogenous levels of DPEP2 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
DPEP2 belongs to the membrane-bound dipeptidase (EC 3.4.13.19) family. These enzymes hydrolyze a variety of dipeptides, including leukotriene D4, the beta-lactam ring of some antibiotics, and cystinyl-bis-glycine (cys-bis-gly) formed during glutathione degradation (Habib et al., 2003 [PubMed 12738806]).[supplied by OMIM, Mar 2008],
Function
catalytic activity:Hydrolysis of dipeptides.,cofactor:Zinc.,enzyme regulation:Inhibited by L-penicillamine.,function:Probable metalloprotease which hydrolyzes leukotriene D4 (LTD4) into leukotriene E4 (LTE4).,similarity:Belongs to the peptidase M19 family.,subunit:Homodimer; disulfide-linked.,
Gene Name
DPEP2 UNQ284/PRO323
Human protein sequence Database
Q9H4A9
Mouse protein sequence database
Q8C255
Rat protein sequence database
Q5M872
Cellular localization
Membrane ; Lipid-anchor, GPI-anchor .
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