Immunogen
Synthesized peptide derived from human ADAT1 AA range: 322-372
Specificity
This antibody detects endogenous levels of ADAT1 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene is a member of the ADAR (adenosine deaminase acting on RNA) family. Using site-specific adenosine modification, proteins encoded by these genes participate in the pre-mRNA editing of nuclear transcripts. The protein encoded by this gene, tRNA-specific adenosine deaminase 1, is responsible for the deamination of adenosine 37 to inosine in eukaryotic tRNA. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010],
Function
cofactor:Binds 1 inositol hexakisphosphate (IP6) per subunit.,function:Specifically deaminates adenosine-37 to inosine in tRNA-Ala.,similarity:Belongs to the ADAT1 family.,similarity:Contains 1 A to I editase domain.,tissue specificity:Ubiquitously expressed.,
Human protein sequence Database
Q9BUB4
Mouse protein sequence database
Q9JHI2
Rat protein sequence database
Tissue expression
Ubiquitously expressed.
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