Immunogen
Synthesized peptide derived from human FIZ1 AA range: 141-191
Specificity
This antibody detects endogenous levels of FIZ1 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes zinc finger protein, which interacts with a receptor tyrosine kinase involved in the regulation of hematopoietic and lymphoid cells. This gene product also interacts with a transcription factor that regulates the expression of rod-specific genes in retina. [provided by RefSeq, Jul 2008],
Function
function:May be a transcriptional repressor of NRL function in photoreceptors. Does not repress CRX-mediated transactivation.,similarity:Contains 11 C2H2-type zinc fingers.,subunit:Interacts with FLT3 cytoplasmic catalytic domain, following receptor stimulation, in a kinase-independent manner. Does not interact with other structurally related receptor tyrosine kinases, including KIT, CSF1R and PDGFR. Interacts with NRL.,tissue specificity:Widely expressed.,
Human protein sequence Database
Q96SL8
Mouse protein sequence database
Q9WTJ4
Rat protein sequence database
Cellular localization
Cytoplasm . Nucleus .
Tissue expression
Widely expressed.
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