Immunogen
Synthesized peptide derived from human EGFL6 AA range: 144-194
Specificity
This antibody detects endogenous levels of EGFL6 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a member of the epidermal growth factor (EGF) repeat superfamily. Members of this superfamily are characterized by the presence of EGF-like repeats and are often involved in the regulation of cell cycle, proliferation, and developmental processes. The gene product contains a signal peptide, suggesting that it is secreted; an EGF repeat region consisting of 4 complete EGF-like repeats and 1 partial EGF-like repeat, 3 of which have a calcium-binding consensus sequence; an arg-gly-asp integrin association motif; and a MAM domain, which is believed to have an adhesive function. This gene is expressed early during development, and its expression has been detected in lung and meningioma tumors. [provided by RefSeq, Jul 2008],
Function
developmental stage:Only detected in fetal tissues.,function:May bind integrin alpha-8/beta-1 and play a role in hair follicle morphogenesis. Promotes matrix assembly.,similarity:Belongs to the nephronectin family.,similarity:Contains 1 MAM domain.,similarity:Contains 5 EGF-like domains.,
Gene Name
EGFL6 MAEG PP648 UNQ281/PRO320
Human protein sequence Database
Q8IUX8
Mouse protein sequence database
Q9JJZ5
Rat protein sequence database
Cellular localization
Secreted, extracellular space, extracellular matrix, basement membrane .
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