Immunogen
Synthesized peptide derived from human FAD1 AA range: 480-530
Specificity
This antibody detects endogenous levels of FAD1 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes the enzyme that catalyzes adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008],
Function
catalytic activity:ATP + FMN = diphosphate + FAD.,cofactor:Magnesium.,domain:The molybdenum cofactor biosynthesis protein-like region may not be functional.,function:Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme.,pathway:Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1.,similarity:In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily.,similarity:In the N-terminal section; belongs to the moaB/mog family.,
Fields
>>Riboflavin metabolism;>>Metabolic pathways;>>Biosynthesis of cofactors
Human protein sequence Database
Q8NFF5
Mouse protein sequence database
Q8R123
Rat protein sequence database
Cellular localization
[Isoform 1]: Mitochondrion matrix .; [Isoform 2]: Cytoplasm.
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