Immunogen
Synthesized peptide derived from human ANO2 AA range: 362-412
Specificity
This antibody detects endogenous levels of ANO2 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
ANO2 belongs to a family of calcium-activated chloride channels (CaCCs) (reviewed by Hartzell et al., 2009 [PubMed 19015192]).[supplied by OMIM, Jan 2011],
Function
function:May act as a calcium-activated chloride channel.,similarity:Belongs to the anoctamin family.,
Gene Name
ANO2 C12orf3 TMEM16B
Fields
>>Olfactory transduction
Human protein sequence Database
Q9NQ90
Mouse protein sequence database
Q8CFW1
Rat protein sequence database
Cellular localization
Cell membrane ; Multi-pass membrane protein .
Tissue expression
Retina, especially in the photoreceptor synaptic terminals.